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Before Patrick Mahomes laced up his cleats for his 2026-2027 NFL regular-season debut, US prediction markets had already cleared a historic benchmark for the opening week of the season.

Two operators alone – Kalshi and Polymarket – topped the combined $1 billion mark in NFL trading activity over the first six days of Week 1, according to numerous measures this week. During the period, Kalshi recorded NFL volume of $983.4 million, according to DeFi Rate, earning the pole position by a large margin. Mahomes and the Kansas City Chiefs thrashed the Denver Broncos 31-10 on Monday Night Football, capping the largest week for prediction markets ever.

Even before the primetime matchup in Kansas City, it became abundantly clear that the industry would shatter previous marks for weekly activity. The AFC West showdown bolstered the already robust totals. Overall, volume for the week hit a record $15.9 billion, according to Bank of America, up 16% from a week earlier.

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Europe, excluding the UK, grew 2%. Overall, regulated revenue for B2B accounted for 83% of overall revenue across the segment, marking 21% growth, compared to unregulated.

Speaking during the follow-up analyst call, Playtech CEO Mor Weizer said regulated revenue would continue to grow, although the company would “continue to support those markets that we believe over time will become regulated”.

“Unregulated is not illegal,” he asserted. “We will continue to support those markets that we believe over time will become regulated.

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Citing U.S. code, the gaming company is pushing for an inter parties review while requesting that the board find the 18 claims in question “unpatentable.”

Patent squabbles, including those pertaining to geolocation services, aren’t unheard of in the online gaming space. How things shake out in the Cantor Fitzgerald/DraftKings spat remains to be seen, but it’s possible the deck is stacked against the gaming company.

The Commerce Department has jurisdiction over the USPTO, meaning Lutnick is the boss of the USPTO Director John Squires. Squires, who became 60th director of the USPTO a year ago, has been publicly effusive in his praise of Lutnick.