Twisted Lab

How to play Twisted Lab

50 Cent previewed the project on Instagram on Sept. 17, 2026, framing the venture as the long-overdue legitimization of a game that always played by its own rules.

“For a hundred years this game lived on the corner,” he said in TCS/JOHNHUXLEY’s press release. “Now it’s got a dealer, a pay table and a seat at the table in a real casino. Same dice, new floor.”

Cee-lo—derived from sì wǔ liù (Chinese for “four-five-six”)—is played with three six-sided dice. Popular among Chinese-American players as early as 1893, it was adopted by hip-hop culture in the late 1970s and became a fixture on the street corners of Harlem, Brooklyn, and the Bronx.

Nas, the Notorious B.I.G., and Jadakiss all referenced the game in their music. Kool G Rap called his 1995 album 4,5,6, and its title track included the line “Headcrack, time to get the bread”—the lyric that most likely inspired 50 Cent’s casino adaptation.

How to play Twisted Lab

During the second half of 2026, prediction markets have endured the wrath of a plethora of state governors, most notably Kathy Hochul of New York.

As the NFL season begins, a state in close proximity to the New England Patriots became the latest to attempt to curb the influence of the trading platforms. On 10 September, one day after the Pats’ season-opening loss to the Seattle Seahawks, Connecticut Governor Ned Lamont addressed the growth of the markets during a speech in downtown Hartford. On the same day, the Connecticut Department of Consumer Protection issued cease-and-desist orders to nine unregulated operators, including Polymarket, Robinhood and Underdog Predict.

“Prediction markets have branded themselves as legal and safe, but the reality is they are not adhering to Connecticut’s consumer protection standards,” Lamont wrote in a statement.

What is Twisted Lab?

Spotlight Sports Group has expanded into the games vertical for the first time through a collaboration with the supplier Engage Games.

Announced on Thursday, the strategic partnership will grant Spotlight’s network of global sportsbook operators access to Engage Games’ bespoke games, each built collaboratively with Spotlight’s partners.

It marks Spotlight’s first expansion into gaming, combining the company’s global product and content distribution with Engage Games’ platform and track record in free-to-play and pay-to-play games.